Green tea extract
Usually sold onAntioxidant activity
Mechanistic claim signalEngages gut protein-digestion and bile acid metabolism pathways.
Mechanism of action evidence for your ingredient, in eight weeks.
MOA Mechanism of actionSSG 2026 promotion · valid until November 16, 2026
From the team behind two NASA-funded biology missions to the International Space Station.
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| Comparison | Without MOA characterization | With MOA characterization |
|---|---|---|
| What your paperwork proves | Identity and purity. Every competitor’s CoA proves the same. | Identity and purity, plus what your ingredient does in a living organism. |
| How buyers compare you | Price per kilo. | Mechanism evidence first, then price. |
| “Is it safe?” | Contaminant limits on your CoA. | Acute toxicity at a human-relevant dose (ToxRadar™).* |
| “What does it do?” | Published studies on the botanical, which any competitor can cite too. | The pathways your ingredient activates or suppresses, mapped to human orthologues. |
| Your sales story | The category’s usual benefit (“an antioxidant”). | Your ingredient’s own mechanism, sometimes one nobody expected. |
| Claim language for brands | None. Brands write their own and carry the risk. | Mechanistic claim signals with the regulatory qualifier, ready for brands to work from. |
| How brands find you | Trade shows, distributors, cold outreach. | Brands searching TrueBioactives™ by mechanism. |
* ToxRadar™ results are invertebrate toxicity data and do not substitute for a mammalian safety package.
Each of these turned out to act through a different route than the one it is known for. Knowing the real mechanism is the edge a buyer can’t get from a price list.
Usually sold onAntioxidant activity
Mechanistic claim signalEngages gut protein-digestion and bile acid metabolism pathways.
Usually assumedActs on gut tissue directly
Mechanistic claim signalSupports muscle health pathways through the gut–muscle axis.
Usually known forNeuronal pathways
Mechanistic claim signalEngages longevity pathways in addition to neuronal signaling pathways.
Findings from TrueBioactives™ MOA characterizations, shown without supplier names. Preclinical pathway evidence (C. elegans, BioSēq™); not statements of clinical efficacy.
Your ingredient is dosed into living C. elegans, the whole organism rather than isolated cells. ToxRadar™ reads acute toxicity at a human-relevant dose. BioSēq™ reads every gene that changes and maps each pathway to its human counterpart.
CoA or label review.
Acute toxicity at a human-relevant dose. Does not substitute for a mammalian safety package.
Level of bioactivity assessed using gene expression data.
Activated or suppressed, mapped to human orthologues.
Pathway combinations interpreted into benefit themes.
Claim signals with the mandatory regulatory qualifier.
Open a TrueBioactives™ account and upload your CoAs.
Send 10 grams of each ingredient.
View your MOA characterization on TrueBioactives™, L1 through L6.
Choose what brands see. Nothing is published until you release it.
Opening an account and uploading CoAs is free. Each tested ingredient receives the full six-level MOA characterization, from identity and ToxRadar™ safety through mechanistic claims.
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| What’s included | TrueBioactives™ accountStart hereFree | Single1 ingredient$5,000$5,000 per ingredient | Three-pack3 ingredients$12,000$4,000 per ingredientSave $3,000 | Five-pack5 ingredients$18,000$3,600 per ingredientSave $7,000 |
|---|---|---|---|---|
| Your account | ||||
| Account activation | ✓ | ✓ | ✓ | ✓ |
| CoA uploadsUnlimited, for every ingredient you supply | ✓ | ✓ | ✓ | ✓ |
| L1IdentityCoA or label review | ✓ | ✓ | ✓ | ✓ |
| MOA characterization, per tested ingredient * | ||||
| L2Acute toxicity assessmentToxRadar™ acute toxicity at a human-relevant dose. Does not substitute for a mammalian safety package. | — | ✓ | ✓ | ✓ |
| L3BioactivityLevel of bioactivity assessed using gene expression data | — | ✓ | ✓ | ✓ |
| L4PathwaysPathways with direction, mapped to human orthologues | — | ✓ | ✓ | ✓ |
| L5Benefit signalsPathway combinations interpreted into benefit themes | — | ✓ | ✓ | ✓ |
| L6Mechanistic claimsClaim signals in mechanism language, carrying the mandatory regulatory qualifier | — | ✓ | ✓ | ✓ |
| Ingredients MOA characterized | — | 1 | 3 | 5 |
* The eight-week timeline starts once we receive your ingredient samples, 10 grams per ingredient, and your payment.
One year of access to your ingredients’ evidence on TrueBioactives™.
If the yearly fee is not paid: access to Evidence Studio™ and your reports ends 90 days after your MOA characterization data is delivered, and the high-level MOA characterization of your ingredients is no longer visible to brands. Reports can be downloaded during the 90 days and are yours to keep.
Promotion terms. Open to ingredient suppliers worldwide. Prices apply to orders placed on or before November 16, 2026. Terms are confirmed in your MOA characterization agreement.
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